Welcome to Ozone Therapies Group

At Ozone Therapies Group, we’re redefining what’s possible in both clinical ozone therapy and cosmetic skincare. Founded and led by Dr. Mark T. Weiser, DDS, our family-run company brings together over two decades of research, education, and hands-on innovation in the field of Ozone Therapy.

From our signature ozonated skincare line to our nationally recognized medical and dental conferences, everything we do is rooted in science, integrity, and results. We’re proud to support practitioners and consumers alike in accessing the powerful benefits of ozone—from cellular regeneration to radiant skin and beyond.

Frontiers 10 Ozone Conference – coming soon!

Our 10th annual conference will take place November 5-7, 2026 Location TBA!

Shop Our Ozonated Skincare Line

Transform your daily routine with our patent-stabilized ozonated glycerin formulas, developed for use across personal, clinical, and professional settings. From OG-S to OG Paste, our products are safe, shelf-stable, and trusted by top integrative doctors around the world.

Perfect for skin health, oral care, wound recovery, and post-procedure support.

Explore the collection

We invite you to experience the future of wellness.
Join us. Shop. Learn. Lead.

OG-S Skin Gel
Sale Price: $75.00 Original Price: $99.00

All-in-One Hydration Gel Infused with Stabilized Ozone Technology

OG-S Skin Gel delivers full-spectrum skin support in one simple step. Formulated in Japan using a patented method of ozone stabilization, this lightweight gel combines stabilized ozonated glycerin with skin-repairing ingredients including ceramides, amino acids, collagen, hyaluronic acid, and Tamatsukuri Onsen Water.

Created for both professionals and personal users, this gel absorbs quickly, leaves no residue, and is clinically tested for sensitive and reactive skin. It’s ideal for anyone seeking barrier repair, hydration, and antioxidant support—without layering multiple products.

✦ Key Features:

  • Combines toner, serum, and moisturizer into one

  • No ozone odor, no refrigeration required

  • Rich in bioactive peptides, natural lipids, and HA complexes

  • Designed for all skin types, including hypersensitive and pediatric

  • Absorbs fast with a silky, lightweight finish

  • Ideal for simplifying ozone skincare in clinical or home settings

Use: Apply 1–2 pumps after cleansing. Use day or night for deeply replenished, balanced skin.

Pure OG Paste
Sale Price: $66.00 Original Price: $88.00

High-Adherence Ozone Delivery – Developed for Targeted, Lasting Application

Pure OG Paste is a high-viscosity, concentrated form of stabilized ozonated glycerin, created for long-lasting adherence and precise placement. Built on the same patented platform as Pure OG-S, this formula offers a thicker texture ideal for localized use, prolonged contact, or professional settings where ozone needs to stay active and stable.

Crafted in Japan and perfected over two decades, the paste is odorless, shelf-stable at room temperature, and contains no artificial ingredients. Its smooth, ointment-like consistency supports intensive hydration and acts as a functional base for a wide variety of applications.

✦ Why It’s Trusted by Clinics and Practitioners:

  • High-viscosity formula for targeted use and extended contact

  • Delivers active ozone without odor, irritation, or mess

  • No refrigeration needed—stays potent for 3 years

  • Ideal for slow-release ozone exposure or overnight use

  • No preservatives, synthetics, or added fragrance

  • Made with 100% natural-grade glycerin

Use: Apply a small amount where deeper support or stronger adhesion is needed. Integrates easily into personal or professional care protocols.

Pure OG-S
$88.00

Stabilized Ozonated Glycerin Gel – Precision Formulated, Broadly Versatile

Pure OG-S is a next-generation ozonated glycerin gel, engineered through a patented stabilization process developed over 20 years in Japan. This water-soluble, syrup-like gel delivers the active power of ozone without odor, refrigeration, or degradation—designed for professionals and individuals seeking a clean, effective way to integrate ozone into protocols or daily routines.

Unlike traditional ozonated oils that break down quickly and carry a strong scent, Pure OG-S uses 100% natural-grade glycerin to safely and stably hold ozone in solution. It remains shelf-stable for up to 3 years at room temperature, with a smooth, non-irritating texture that’s suitable for even the most sensitive applications.

✦ Why Professionals and Consumers Choose It:

  • Advanced ozone delivery system—no mixing, no bubbling

  • Backed by 20 years of clinical R&D in Japan

  • Stable for 3 years with no refrigeration required

  • Clean, smooth application with a slightly sweet finish

  • Water-soluble and easy to incorporate into custom protocols

  • No preservatives, no scent, no artificial ingredients

Use: Apply as needed in your preferred modality or setting. Suitable for skin, mucosal, and other professional applications.