Alberto Balbin


Efficacy of peri-radicular ozone in radiculopathies

Alberto Balbin Hurtado, Silvia Menéndez Cepero, Miguel Ángel Montoya Diaz

Since pain has always been the most important symptom with which medicine has to face, neuropathic pain generated exclusively by damage or change in the central or peripheral nervous system is caused by the inflammation of a nerve or its terminal nerve endings. Pharmacotherapy has been the cornerstone in the treatment of neuropathic pain. Different classes of medications have been shown to be safe and effective in relieving pain in patients with neuropathies, despite the presence of adverse effects often seen with their use. More and more medical ozone is used in the treatment of pain. The effectiveness, safety and good tolerance of ozone, both infiltrated and administered systemically, justify the extension of its use in recent years. Taking into account the increase in the use of Ozone in the treatment of pain, we carried out a study with the objective of demonstrating the effectiveness in the use of peri-radicular ozone in radiculopathies. A total of 39 patients with a history of neuropathic pain with more than three months of evolution who underwent conventional drug therapy and with electrophysiological studies showing signs of chronic radiculopathy were evaluated. The antineuritics were administered to 19 patients combined with root ozone (13 pts.) And uniquely (6 pts.) And 20 pts. (51.3%) were applied only root ozone. Our hypothesis was that adding to the usual symptomatic treatment, the use of ozone, exploiting its regulatory properties of oxygen metabolism, chemical mediators of inflammation and pain, would allow us to achieve a more early and significant improvement of pain symptoms in this Type of neuropathic pain, coupled with an improvement in neuronal function. The affections of the spine causing neuropathic pain in our study group were disc herniation, lumbar degeneration associated to narrow canal by ligamentous and facetary hypertrophy and grade III vertebral listesis, as well as postsurgical fibrosis and post-instrumentation radiculitis. Adverse events occurred in both groups but with a slightly higher frequency in the group receiving antineuritics as monotherapy. Efficacy was demonstrated in the use of peri-radicular ozone in radiculopathies. Herniated disc was the nosological entity that caused radiculopathy more frequently at the lumbar level in the sample studied. There were more adverse effects in the group of patients treated with antineuritics alone, in relation to the combined treatments with Ozone. A higher clinical course was observed in patients treated with ozone either in combination with antineuritics or only in relation to those treated with antineuritics alone. There was an electrophysiological improvement in the studied sample, being this higher in the group treated with ozone in relation to the group treated only with antineuritics.